Semax

Semax 10 mg is supplied by PrimeTime BioLabs as a lyophilized, research-grade peptide intended for laboratory use. The listing reflects a 10 mg unit quantity per vial, packaged for stability and traceability rather than for consumer handling. Scientific identity. Semax is documented in independent chemical references as a synthetic heptapeptide with the amino acid sequence Met-Glu-His-Phe-Pro-Gly-Pro (one-letter notation: MEHFPGP). It carries the CAS registry number 80714-61-0, the molecular formula C₃₇H₅₁N₉O₁₀S, and a molecular weight of approximately 813.9 g/mol, as reported by PubChem and multiple peptide reference sources. These figures describe the free peptide as characterized in the scientific literature; they are independent chemical-reference values and are separate from the lot-specific purity and identity results reported on this product's Certificate of Analysis. Structural classification. The Semax sequence is built from the ACTH(4-7) fragment (Met-Glu-His-Phe) with a Pro-Gly-Pro tripeptide added at the C-terminus. Because of this, the compound is commonly referred to in the literature as an ACTH(4-10)-related analog, and more precisely as ACTH(4-7)-PGP. The added tripeptide is the structural feature most often cited in the literature as contributing to the molecule's resistance to enzymatic breakdown relative to the native ACTH fragment. This is a chemistry-and-structure distinction, not a statement about what the compound does in a research setting — see Research Focus & Mechanism Overview below. Physical format. As supplied by PrimeTime BioLabs, Semax ships as a lyophilized (freeze-dried) powder in a sealed, light-protected vial, with a printed lot number for batch traceability. Each unit includes handling and reconstitution reference information intended for laboratory use. Quantity and unit. This listing corresponds to a single 10 mg vial. PrimeTime BioLabs does not publish a minimum order requirement for this product; bulk pricing for qualified research institutions is available on request through the contact page. Documentation. A Certificate of Analysis (COA) is issued for the specific lot shipped, listing the batch number, reported purity, and analysis date. The current lot on file is batch PTBL08312026, reporting 99% purity, analyzed 9/2/2026. Because COAs are lot-specific, the batch number on the physical vial received should always be checked against the batch number on the downloaded COA before the material is used in any research protocol. Scope of use. This product is formulated and sold strictly for laboratory and in-vitro research applications by qualified professionals. It is not a drug, dietary supplement, food, or cosmetic, and it is not evaluated or approved by the FDA for any use. See the Compliance Notice tab for the full research-use restriction.

Semax has been studied in the scientific literature for several decades, most extensively in Russian pharmacological and neurobiological research, where it is described as a synthetic ACTH-related peptide investigated for effects on neurotrophic signaling and central nervous system activity in animal and cellular models. Chemical and structural basis of the research interest. Because Semax is derived from the ACTH(4-7) fragment with a Pro-Gly-Pro extension, researchers have used it as a tool to probe structure–activity relationships that differ from those of full-length or unmodified ACTH. Independent literature identifies this modification as relevant to peptide stability rather than to melanocortin receptor activation of the kind associated with native ACTH — a distinction that matters for interpreting mechanism-of-action studies, since Semax's research profile is not simply that of a shortened ACTH molecule. Neurotrophin-related research. A recurring theme in the published literature is Semax's interaction with brain-derived neurotrophic factor (BDNF) signaling pathways. Studies in rodent models have reported changes in BDNF expression in specific brain regions following Semax administration, and cellular studies have examined neurotrophin-related gene expression in response to the peptide. These findings describe experimental observations in specific animal or cellular systems — they are mechanistic research data, not a demonstrated outcome for any individual, human or otherwise, and they do not describe an effect of this specific PrimeTime BioLabs lot. Gene-expression and transcriptomic research. Genome-wide expression studies in rodent models of cerebral ischemia have examined how Semax and its constituent Pro-Gly-Pro fragment influence gene-expression patterns associated with immune and inflammatory signaling in brain tissue following induced injury. This line of research has been used to explore potential neuroprotective mechanisms at the molecular level, again in defined animal-injury models rather than in unmodified physiological conditions. Behavioral and physiological research models. Separate lines of published animal research have examined Semax in models related to anxiety-like behavior, nociception, and stress response, typically using standardized behavioral assays (such as elevated-maze paradigms) in rodents. Historical human research, largely conducted outside the United States, has also examined Semax in clinical contexts; this body of work varies substantially in study design, sample size, era, formulation, and route of administration, and does not establish safety, efficacy, or an approved use for this or any research peptide sold in the United States. Why this matters for researchers evaluating this listing. The literature summarized above describes what has been studied about the Semax molecule generally — not a property, benefit, or guaranteed outcome of the PrimeTime BioLabs Semax 10 mg product specifically. Findings from a given animal model, cell line, dose, or historical clinical study do not transfer automatically to a different research design, species, or exposure. Researchers designing their own protocols should consult the primary literature directly and evaluate its applicability to their specific model system. What this section does not claim. This overview does not state that Semax improves memory, cognition, focus, or mood; treats anxiety, depression, ADHD, or any other condition; or produces any particular effect in a human being. It describes documented research topics associated with the Semax molecule in the published literature, for the benefit of researchers evaluating whether this material is relevant to their own work.

PrimeTime BioLabs documents each lot of Semax 10 mg with independent, third-party analytical testing before it is made available for purchase. Testing methods used. Each batch undergoes high-performance liquid chromatography (HPLC) and mass spectrometry (MS) analysis. HPLC is used to assess the purity of the sample by separating and quantifying its chemical components, while mass spectrometry is used to help confirm molecular identity by measuring the mass of the compound and detecting mass-related impurities or degradation products. What this testing establishes. Together, HPLC and MS testing can support two specific claims about a given lot: (1) an estimate of chemical purity relative to other detectable components in the sample, and (2) evidence consistent with the expected molecular identity of the peptide. The current lot on file for this listing, batch PTBL08312026, was analyzed on 9/2/2026 and reports 99% purity. What this testing does not establish. Analytical purity and identity testing, on their own, do not establish sterility, endotoxin status, biological activity, safety for any living organism, or therapeutic effectiveness. A high purity result describes the chemical composition of the sample — it says nothing about what happens when that compound is introduced into a biological system. PrimeTime BioLabs does not represent HPLC/MS purity testing as evidence of safety or efficacy for any use. Certificate of Analysis (COA) access. A COA is issued for the specific lot shipped and is available for download directly from this listing and from the buyer's account after purchase. The COA states the batch number, reported purity, and analysis date, and should be checked against the lot number printed on the physical vial received. If the batch number on a vial does not match the batch number on the downloaded COA, researchers should contact PrimeTime BioLabs support before using the material. Storage-related quality notes. Lyophilized (freeze-dried) peptides are inherently more stable than reconstituted solutions. As a general reference for lyophilized peptide handling, unopened vials are best kept frozen and protected from light, while any reconstituted solution should be kept refrigerated and used within the timeframe specified on the corresponding COA. Researchers should always follow the specific storage guidance on their own vial and COA rather than generic peptide-storage assumptions, since stability can vary by formulation and salt form. Distinguishing this listing from other Semax products. Not all commercially available "Semax" products are chemically identical. Some suppliers offer modified derivatives — such as N-acetylated, amidated forms sold under different trade names — or intranasal liquid formulations, which differ in chemical structure, format, and testing profile from the lyophilized powder listed here. Researchers comparing suppliers or literature should confirm which exact chemical form and physical format is being discussed, since findings, specifications, and COA data for one form do not automatically apply to another.

Semax 10 mg is sold by PrimeTime BioLabs strictly for laboratory and in-vitro research use by qualified professionals. This product is not a drug, dietary supplement, food, or cosmetic. It has not been evaluated by the U.S. Food and Drug Administration, and it is not intended for human or animal consumption, diagnosis, treatment, cure, or prevention of any disease or condition. No content on this listing should be interpreted as dosing, administration, or treatment guidance for human or animal use. Any handling or reconstitution reference information provided with this product is intended solely to support laboratory research procedures and is not a recommendation for personal or clinical use. By purchasing this product, the buyer represents that they are acquiring it for legitimate research purposes, that they are qualified to handle laboratory research chemicals safely, and that they understand and accept the research-use-only restriction described here and in PrimeTime BioLabs' site-wide Terms & Conditions and Medical Disclaimer.